Description

3-Methylglutaric Acid Di(Trimethylsilyl) Ester is a specialized organosilicon derivative of 3-methylglutaric acid, serving as a key protected intermediate in advanced organic synthesis. This compound is valued for its role in introducing the 3-methylglutarate moiety while offering enhanced stability and solubility in non-polar media through its silyl ester groups. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and novel materials.

Application

• Pharmaceutical Intermediate: Used in the multi-step synthesis of drug candidates and active pharmaceutical ingredients (APIs), particularly where protection of carboxylic acid groups is required.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and plant growth regulators with specific activity profiles.
• Fine Chemical Production: A key precursor in the manufacture of specialty chemicals, flavors, fragrances, and advanced polymer additives.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex organic molecules, leveraging the silyl ester's reactivity and protective nature.
• Material Science Research: Investigated for use in the development of novel silicon-containing polymers and hybrid organic-inorganic materials.
• Cross-Coupling Reactions: Can act as a substrate in various metal-catalyzed coupling reactions to form new carbon-carbon bonds.

Basic Information

Product Name	3-Methylglutaric Acid Di(Trimethylsilyl) Ester
CAS No.	55517-41-4
Molecular Formula	C14H30O4Si2
Molecular Weight	318.56 g/mol
Synonyms	Bis(trimethylsilyl) 3-Methylglutarate; 3-Methylpentanedioic Acid Bis(trimethylsilyl) Ester; Di(trimethylsilyl) 3-Methylglutarate; 3-Methylglutaric Acid Bis(trimethylsilyl) Ester; TMS Ester of 3-Methylglutaric Acid; 3-Methylglutaric Acid Di-TMS Ester; 55517-41-4; 3-Methylpentanedioic acid, 1,5-bis(trimethylsilyl) ester
EINECS	Contact for details

Quality Control

Our 3-Methylglutaric Acid Di(Trimethylsilyl) Ester is produced under controlled conditions to ensure high chemical purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical properties is provided with every shipment. We adhere to cGMP principles where applicable to support its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.