Description

2-o-Methyl-1-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-β-D-Glucopyranose is a key protected carbohydrate intermediate, specifically a fully silylated methyl glucoside derivative. Its value lies in providing a stable, non-reactive scaffold for the selective deprotection and functionalization of specific hydroxyl groups during complex oligosaccharide and glycoconjugate synthesis. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel glycosylated drugs, and in advanced organic synthesis for building sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex carbohydrate-based active pharmaceutical ingredients (APIs) and prodrugs.
• Glycochemistry Research: Used as a starting material or protected intermediate for studying glycosylation reactions and synthesizing oligosaccharides with precise stereochemistry.
• Glycoconjugate Synthesis: Enables the production of glycopeptides, glycolipids, and other conjugates for biochemical research and diagnostic applications.
• Chemical Biology Probes: Acts as a precursor for labeled sugars used to study metabolic pathways and cellular recognition processes.
• Specialty Chemical Manufacturing: Employed in the custom synthesis of high-value, chirally pure compounds for the fine chemical industry.

Basic Information

Item	Details
Product Name	2-o-Methyl-1-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-β-D-Glucopyranose
CAS No.	55515-37-2
Molecular Formula	C19H46O6Si4
Molecular Weight	482.90 g/mol
Synonyms	Methyl 2,3,4,6-Tetra-O-trimethylsilyl-β-D-glucopyranoside; Methyl β-D-Glucopyranoside 2,3,4,6-Tetrakis(trimethylsilyl) Ether; 2-O-Methyl-1,3,4,6-tetra-O-trimethylsilyl-β-D-glucopyranose; β-D-Glucopyranose, 2-O-methyl-1,3,4,6-tetrakis-O-(trimethylsilyl)-; TMS-protected methyl β-D-glucoside; Methyl β-D-glucoside per(trimethylsilyl) ether
EINECS	Contact for details

Quality Control

Our 2-o-Methyl-1-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-β-D-Glucopyranose is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting research and synthesis standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment, ideally under an inert atmosphere such as nitrogen or argon for long-term storage to prevent hydrolysis of the silyl protecting groups.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.