Description

3-o-Methyl-1-O,2-O,4-O,6-o-Tetrakis(Trimethylsilyl)-β-D-Glucopyranose is a highly functionalized, fully protected monosaccharide derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a chemically stable, non-participating scaffold for the selective manipulation of carbohydrate hydroxyl groups, enabling precise stereochemical control in complex molecule assembly. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the synthesis of nucleosides, complex glycoconjugates, and other bioactive molecules where regioselective protection is paramount.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of modified nucleoside analogs used in antiviral and anticancer therapies.
• Glycochemistry Research: Serves as a protected glycosyl donor or acceptor for the controlled synthesis of oligosaccharides and glycoconjugates.
• Agrochemical Synthesis: Intermediate in the production of complex, biologically active molecules with carbohydrate motifs for crop protection.
• Chemical Biology Probes: Used to create labeled or modified sugars for studying biological recognition and metabolic pathways.
• Process Development: Enables scalable, high-yield routes to complex natural products and their derivatives in process chemistry.
• Material Science: Potential precursor for specialty polymers and surfactants with tailored properties derived from sugar chemistry.

Basic Information

Product Name	3-o-Methyl-1-O,2-O,4-O,6-o-Tetrakis(Trimethylsilyl)-β-D-Glucopyranose
CAS No.	55515-36-1
Molecular Formula	C19H46O6Si4
Molecular Weight	482.90 g/mol
Synonyms	1,2,4,6-Tetra-O-trimethylsilyl-3-O-methyl-β-D-glucopyranose; 3-O-Methyl-1,2,4,6-tetra-O-(trimethylsilyl)-β-D-glucopyranose; β-D-Glucopyranose, 3-O-methyl-1,2,4,6-tetrakis-O-(trimethylsilyl)-; 3-O-Methyl-1,2,4,6-tetra-O-trimethylsilyl-β-D-glucopyranose; Fully Protected 3-O-Methyl-D-Glucose; TMS-protected 3-O-Methylglucose; Per-TMS 3-O-Methyl-β-D-glucopyranose
EINECS	Contact for details

Quality Control

Our production of 3-o-Methyl-1-O,2-O,4-O,6-o-Tetrakis(Trimethylsilyl)-β-D-Glucopyranose adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR (1H and 13C), and mass spectrometry, to confirm identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Store away from sources of heat and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.