Description

4-Hydroxythieno[2,3-B]Pyridine-5-Carboxylic Acid Ethyl Ester is a high-value heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its fused thienopyridine core imparts unique biological and electronic properties. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for creating new molecules with targeted functionalities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for enhanced bioactivity.
• Material Science: Serves as a building block for organic electronic materials, such as organic semiconductors and light-emitting diodes (OLEDs), due to its electron-rich fused ring system.
• Chemical Synthesis: Employed as a versatile scaffold in medicinal and combinatorial chemistry for constructing complex molecular libraries.
• Academic & R&D: Utilized in university and corporate research laboratories for studying heterocyclic chemistry and reaction mechanisms.

Basic Information

Product Name	4-Hydroxythieno[2,3-B]Pyridine-5-Carboxylic Acid Ethyl Ester
CAS No.	55503-31-6
Molecular Formula	C11H9NO3S
Molecular Weight	235.26 g/mol
Synonyms	Ethyl 4-Hydroxythieno[2,3-b]pyridine-5-carboxylate; 4-Hydroxythieno[2,3-b]pyridine-5-carboxylic Acid Ethyl Ester; Thieno[2,3-b]pyridine-5-carboxylic acid, 4-hydroxy-, ethyl ester; 5-(Ethoxycarbonyl)-4-hydroxythieno[2,3-b]pyridine; 4-Hydroxy-thieno[2,3-b]pyridine-5-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 4-Hydroxythieno[2,3-B]Pyridine-5-Carboxylic Acid Ethyl Ester is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.