Description

α-(Methoxyimino)Benzenepropanoic Acid Trimethylsilyl Ester is a specialized organosilicon reagent featuring a protected carboxylic acid group. This compound is valued for its role as a key synthetic intermediate in the preparation of complex organic molecules, particularly in pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for constructing advanced molecular scaffolds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a protected carboxylic acid functionality.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its unique structure contributes to specific biological activity.
• Peptide Mimetics & Prodrug Development: Serves as a precursor for creating peptide analogs and prodrug formulations designed for enhanced stability and bioavailability.
• Material Science Research: Employed in the development of novel organic and hybrid materials, including specialty polymers and liquid crystals.
• Cross-Coupling Reactions: Acts as a substrate or reagent in palladium-catalyzed cross-coupling reactions for carbon-carbon bond formation.
• Academic & Industrial R&D: A valuable tool for methodological development and exploratory synthesis in organic chemistry laboratories.

Basic Information

Item	Details
Product Name	α-(Methoxyimino)Benzenepropanoic Acid Trimethylsilyl Ester
CAS No.	55494-13-8
Molecular Formula	C13H19NO3Si
Molecular Weight	265.38 g/mol
Synonyms	Trimethylsilyl 3-(Methoxyimino)-3-phenylpropanoate; 3-(Methoxyimino)-3-phenylpropanoic Acid Trimethylsilyl Ester; (E/Z)-α-(Methoxyimino)benzenepropanoic Acid TMS Ester; Phenylpropanoic Acid, α-(methoxyimino)-, trimethylsilyl ester; TMS Ester of α-(Methoxyimino)hydrocinnamic Acid
EINECS	Contact for details

Quality Control

Our production of α-(Methoxyimino)Benzenepropanoic Acid Trimethylsilyl Ester adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.