Description

(E)-2-Hexenedioic Acid Bis(Trimethylsilyl) Ester is a high-purity silyl ester derivative of a hexenedioic acid, serving as a valuable protected intermediate and reagent in advanced organic synthesis. This compound is crucial for introducing functional groups under mild conditions while protecting sensitive carboxylic acid moieties from unwanted side reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates, particularly where protection of dicarboxylic acid functionalities is required.
• Agrochemical Synthesis: Serves as a key building block in the production of advanced herbicides, fungicides, and plant growth regulators.
• Polymer & Material Science: Employed as a monomer or modifying agent in the development of specialty polymers, coatings, and advanced materials with tailored properties.
• Organic Synthesis Reagent: Acts as a versatile reagent for cross-coupling reactions, carbon-carbon bond formation, and other transformations in fine chemical production.
• Liquid Crystal & Electronic Chemicals: Utilized in the synthesis of precursors for liquid crystal displays (LCDs) and other electronic materials.
• Flavor & Fragrance Industry: Can be used as an intermediate in the synthesis of specific aroma chemicals and flavoring agents.
• Academic & Industrial Research: A valuable tool for methodological development and exploring new synthetic pathways in chemistry laboratories.

Basic Information

Product Name	(E)-2-Hexenedioic Acid Bis(Trimethylsilyl) Ester
CAS No.	55494-10-5
Molecular Formula	C12H26O4Si2
Molecular Weight	290.51 g/mol
Synonyms	2-Hexenedioic Acid, Bis(trimethylsilyl) Ester, (E)-; (E)-2-Hexenedioic Acid Bis(trimethylsilyl) Ester; Bis(trimethylsilyl) (E)-2-Hexenedioate; 2-Hexenedioic Acid Bis(trimethylsilyl) Ester; Trimethylsilyl (E)-2-Hexenedioate; Silyl Ester of 2-Hexenedioic Acid; 55494-10-5; (E)-Muconic Acid Bis(TMS) Ester
EINECS	Contact for details

Quality Control

Our (E)-2-Hexenedioic Acid Bis(Trimethylsilyl) Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to current Good Manufacturing Practices (cGMP) where applicable. Each lot is comprehensively analyzed using advanced techniques including GC, HPLC, NMR, and IR spectroscopy. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening containers to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.