Description

[(Benzyloxy)Imino]Acetic Acid Trimethylsilyl Ester is a specialized organosilicon reagent featuring a protected oxime-acetate functional group. This compound is valued for its role as a versatile synthetic intermediate, particularly in the construction of complex molecules and heterocycles. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications requiring selective protection and functional group manipulation.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing β-lactam or other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where its functional group serves as a precursor to specific bioactive motifs.
• Peptide Mimetics & Conjugate Chemistry: Employed in the preparation of peptide analogs and bioconjugates, leveraging the reactivity of the activated ester and protected oxime.
• Material Science Research: Serves as a precursor or modifying agent in the development of specialty polymers and silicon-based hybrid materials.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis, including studies on silylation, protection/deprotection strategies, and C–N bond formation.

Basic Information

Product Name	[(Benzyloxy)Imino]Acetic Acid Trimethylsilyl Ester
CAS No.	55494-08-1
Molecular Formula	C₁₄H₂₁NO₃Si
Molecular Weight	279.41 g/mol
Synonyms	Acetic acid, [(benzyloxy)imino]-, trimethylsilyl ester; Trimethylsilyl [(benzyloxy)imino]acetate; (Benzyloxyimino)acetic acid trimethylsilyl ester; O-Benzylhydroxylaminoacetic acid trimethylsilyl ester; TMS ester of (benzyloxyimino)acetic acid; N-(Benzyloxy)glyoxylate trimethylsilyl enol ether; [(Benzyloxy)imino]acetoxytrimethylsilane
EINECS	Contact for details

Quality Control

Our production of [(Benzyloxy)Imino]Acetic Acid Trimethylsilyl Ester adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is analyzed via modern spectroscopic and chromatographic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting compliance with research and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.