Description

Octanoic Acid Trimethylsilyl Ester is a versatile organosilicon derivative of caprylic acid, primarily used as a key silylating agent and synthetic intermediate. Its value lies in its ability to protect reactive functional groups, such as hydroxyls and carboxylic acids, during complex multi-step organic syntheses. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for advanced material development.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, particularly for protecting sensitive carboxyl groups during reaction sequences.
• Derivatization Agent for Gas Chromatography (GC): Employed to silylate polar compounds (e.g., fatty acids, alcohols) to improve their volatility and thermal stability for accurate GC and GC-MS analysis.
• Agrochemical Synthesis: Serves as a building block in the production of advanced pesticides, herbicides, and plant growth regulators.
• Polymer & Material Science: Acts as a monomer or modifying agent in the synthesis of silicone-based polymers and specialty materials with tailored surface properties.
• Organic Synthesis Reagent: A crucial reagent for introducing the trimethylsilyl (TMS) protecting group in multi-step laboratory and industrial-scale syntheses.
• Flavor & Fragrance Industry: Utilized in the controlled synthesis of esters and other compounds used in creating specific flavor and aroma profiles.

Basic Information

Product Name	Octanoic Acid Trimethylsilyl Ester
CAS No.	55494-06-9
Molecular Formula	C₁₁H₂₄O₂Si
Molecular Weight	216.40 g/mol
Synonyms	Caprylic Acid Trimethylsilyl Ester; Trimethylsilyl Octanoate; n-Octanoic Acid Trimethylsilyl Ester; TMS Caprylate; Trimethylsilyl Caprylate; Silyl Octanoate; Octanoic Acid, Trimethylsilyl Ester; 1-[(Trimethylsilyl)oxy]-1-oxooctane
EINECS	Contact for details

Quality Control

Our Octanoic Acid Trimethylsilyl Ester is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (IR, NMR), to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.415 - 1.425
Density (g/mL at 20°C)	0.86 - 0.88

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.