Description

n-(1-Oxohexyl)Glycine Trimethylsilyl Ester is a specialized organosilicon-protected amino acid derivative, primarily used as a key synthetic intermediate in advanced organic synthesis. Its value lies in providing a protected glycine moiety with a lipophilic cap, facilitating peptide coupling reactions and the synthesis of modified amino acids under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing novel bioactive compounds and complex organic molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel peptide-based drugs and prodrugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate modified glycine residues.
• Agrochemical Research: Serves as an intermediate in the development of new herbicides, fungicides, and plant growth regulators with amino acid backbones.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, chiral auxiliaries, and complex organic ligands.
• Bioconjugation Chemistry: Useful for creating labeled amino acids or peptides for diagnostic and research applications.
• Material Science: Potential precursor for synthesizing functionalized surfaces or silicon-containing polymers.

Basic Information

Product Name	n-(1-Oxohexyl)Glycine Trimethylsilyl Ester
CAS No.	55494-05-8
Molecular Formula	C11H23NO3Si
Molecular Weight	245.39 g/mol
Synonyms	N-Hexanoylglycine Trimethylsilyl Ester; Trimethylsilyl N-(1-oxohexyl)glycinate; Glycine, N-(1-oxohexyl)-, trimethylsilyl ester; N-Caprolylglycine Trimethylsilyl Ester; (Trimethylsilyl) 2-(hexanamido)acetate; 2-(Hexanamido)acetic acid trimethylsilyl ester; N-(1-Oxohexyl)glycine TMS ester
EINECS	Contact for details

Quality Control

Our n-(1-Oxohexyl)Glycine Trimethylsilyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can compromise product integrity. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.