Description

(Methoxyimino)Malonic Acid Bis(Trimethylsilyl) Ester CAS NO 55494-03-6 is a specialized organosilicon-protected reagent used in advanced organic synthesis. This compound is valued for its role as a versatile building block, enabling the controlled introduction of the methoxyimino malonate moiety under mild conditions. It is primarily required by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules, heterocycles, and active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and complex heterocyclic compounds.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides requiring specific functional group transformations.
• Peptide Mimetics & Modifications: Facilitates the introduction of malonate-derived structures into peptide backbones for drug discovery.
• Material Science Research: Serves as a precursor for novel organic materials and ligands in catalyst development.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed and other metal-mediated coupling reactions.
• Academic & R&D Laboratories: Essential reagent for methodological development in organic chemistry and total synthesis projects.

Basic Information

Product Name	(Methoxyimino)Malonic Acid Bis(Trimethylsilyl) Ester
CAS No.	55494-03-6
Molecular Formula	C11H25NO4Si2
Molecular Weight	291.50 g/mol
Synonyms	Bis(trimethylsilyl) (methoxyimino)malonate; (Methoxyimino)malonic Acid Bis(trimethylsilyl) Ester; Malonic acid, (methoxyimino)-, bis(trimethylsilyl) ester; Trimethylsilyl (methoxyimino)malonate; O-Methyloxime of Malonic Acid Bis(trimethylsilyl) Ester; (Methoxyimino)bis(trimethylsiloxy)ethane
EINECS	Contact for details

Quality Control

Our (Methoxyimino)Malonic Acid Bis(Trimethylsilyl) Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high chemical purity and identity confirmation. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) after opening to prevent decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.