Description

n-(1-Oxobutyl)Glycine Trimethylsilyl Ester is a specialized organosilicon-protected amino acid derivative, primarily utilized as a key synthetic intermediate in advanced organic synthesis. This compound is valued for its role in facilitating complex peptide coupling and protecting group strategies, enabling the production of high-value fine chemicals and active pharmaceutical ingredients (APIs). It is essential for research and development laboratories, as well as production facilities, in the pharmaceutical, agrochemical, and advanced materials sectors seeking reliable, high-purity building blocks.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel peptide-based drugs and complex organic molecules.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis where the trimethylsilyl ester group acts as a protective moiety for the carboxylic acid functionality.
• Agrochemical Synthesis: Serves as an intermediate in the development of new herbicides, fungicides, and plant growth regulators.
• Chemical Research: Employed in academic and industrial R&D for method development and exploring new synthetic pathways.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals, flavors, and fragrances requiring precise molecular construction.
• Bioconjugation: Potential use in creating modified biomolecules for diagnostic and therapeutic applications.

Basic Information

Product Name	n-(1-Oxobutyl)Glycine Trimethylsilyl Ester
CAS No.	55493-97-5
Molecular Formula	C11H23NO3Si
Molecular Weight	245.39 g/mol
Synonyms	Butyryl-Gly-OTMS; N-Butyrylglycine Trimethylsilyl Ester; Glycine, N-(1-oxobutyl)-, trimethylsilyl ester; 2-[(1-Oxobutyl)amino]acetic acid trimethylsilyl ester; Trimethylsilyl N-butyrylglycinate; TMS-Gly-But; N-Butanoylglycine trimethylsilyl ester
EINECS	Contact for details

Quality Control

Our n-(1-Oxobutyl)Glycine Trimethylsilyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.