Description

2-(Methoxyimino)Butanoic Acid Trimethylsilyl Ester is a specialized organosilicon reagent primarily used as a key synthetic intermediate and protecting group in advanced organic synthesis. This compound is valued for its ability to introduce the methoxyimino functional group under mild conditions, facilitating complex molecule construction. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, as well as in advanced material science for creating functionalized polymers.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex drug molecules, particularly in constructing β-lactam antibiotics and other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the methoxyimino moiety is a key pharmacophore for biological activity.
• Peptide Chemistry: Serves as a protecting group for carboxylic acids during solid-phase and solution-phase peptide synthesis, offering orthogonal deprotection strategies.
• Material Science Precursor: Employed in the development of silicon-containing polymers and hybrid organic-inorganic materials with tailored surface properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for methodology development and the synthesis of novel chemical entities.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value specialty chemicals, flavors, and fragrances requiring precise functional group manipulation.

Basic Information

Product Name	2-(Methoxyimino)Butanoic Acid Trimethylsilyl Ester
CAS No.	55493-93-1
Molecular Formula	C8H17NO3Si
Molecular Weight	203.31 g/mol
Synonyms	Trimethylsilyl 2-(Methoxyimino)butanoate; Butanoic acid, 2-(methoxyimino)-, trimethylsilyl ester; 2-(Methoxyimino)butyric Acid Trimethylsilyl Ester; TMS Ester of 2-(Methoxyimino)butanoic Acid; (Trimethylsilyl) 2-(methoxyimino)butanoate; O-Trimethylsilyl 2-(Methoxyimino)butyrate; 2-Methoxyiminobutyric Acid Trimethylsilyl Ester
EINECS	Contact for details

Quality Control

Our 2-(Methoxyimino)Butanoic Acid Trimethylsilyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and GC and NMR for identity and impurity profiling, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.