Description

Propanoic Acid, 2-(Methoxyimino)-, Trimethylsilyl Ester is a specialized organosilicon derivative of a methoxyimino acid, primarily utilized as a key synthetic intermediate or protecting group reagent in advanced organic synthesis. Its value lies in its ability to introduce the trimethylsilyl (TMS) group, which can modify reactivity, enhance volatility for analysis, or serve as a temporary protective moiety for sensitive functional groups. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Used in the synthesis of complex drug candidates, particularly where the methoxyimino and silyl ester functionalities are required for specific molecular transformations.
• Agrochemical Synthesis: Serves as a building block in the production of advanced pesticides and herbicides, leveraging its reactive sites for constructing heterocyclic or side-chain structures.
• Peptide and Carbohydrate Chemistry: Acts as a protecting group reagent for carboxylic acids during multi-step synthesis of sensitive biomolecules.
• Analytical Derivatization: Employed to silylate compounds for Gas Chromatography-Mass Spectrometry (GC-MS) analysis, improving the volatility and detection of polar analytes.
• Material Science Research: Investigated as a precursor or modifying agent in the development of specialty silicon-containing polymers and coatings.
• Cross-Coupling Reactions: May be utilized in palladium-catalyzed reactions as a coupling partner or as a reagent to generate active organometallic species.

Basic Information

Product Name	Propanoic Acid, 2-(Methoxyimino)-, Trimethylsilyl Ester
CAS No.	55493-92-0
Molecular Formula	C7H15NO3Si
Molecular Weight	189.28 g/mol
Synonyms	2-(Methoxyimino)propanoic Acid Trimethylsilyl Ester; Trimethylsilyl 2-(Methoxyimino)propanoate; α-(Methoxyimino)propionic Acid Trimethylsilyl Ester; (E)-2-Methoxyiminopropionic Acid Trimethylsilyl Ester; TMS Ester of Methoxyiminopropionic Acid; O-Trimethylsilyl 2-Methoxyiminopropionate; Propanoic acid, 2-(methoxyimino)-, 1-(trimethylsilyl) ester
EINECS	Contact for details

Quality Control

Our Propanoic Acid, 2-(Methoxyimino)-, Trimethylsilyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed after opening to minimize exposure to moisture and prevent evaporation. Store away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC or HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.