Description

Trimethyl[(5α-Stigmastan-3β-yl)oxy]silane is a high-purity organosilicon derivative of β-sitosterol, a key phytosterol. This compound is valued for its role as a versatile synthetic intermediate and protecting group reagent in advanced organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, nutraceutical, and fine chemical industries for developing steroidal drugs, bioactive molecules, and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel steroidal drugs and hormone analogs.
• Protecting Group Reagent: Used to protect hydroxyl groups in complex multi-step organic syntheses, particularly for sensitive steroidal compounds.
• Nutraceutical Research: Intermediate in the development and study of modified phytosterols with enhanced bioavailability or specific biological activity.
• Fine Chemical Synthesis: Employed in the production of high-value specialty chemicals, including liquid crystals and advanced materials.
• Bioconjugation Chemistry: Potential use in creating silyl ether derivatives for labeling or modifying biomolecules.
• Academic & Industrial R&D: Serves as a critical reagent in research laboratories for methodological development and exploring new chemical entities.

Basic Information

Product Name	Trimethyl[(5α-Stigmastan-3β-yl)oxy]silane
CAS No.	55493-85-1
Molecular Formula	C32H58OSi
Molecular Weight	486.89 g/mol
Synonyms	β-Sitosterol trimethylsilyl ether; Stigmast-5-en-3β-ol trimethylsilyl ether; 3β-Trimethylsilyloxy-5α-stigmastane; (3β)-Stigmastan-3-ol trimethylsilyl ether; 24-Ethylcholest-5-en-3β-ol TMS ether; TMS-β-sitosterol; Silane, trimethyl[(3β,5α)-stigmastan-3-yl]oxy]-; 5α-Stigmastan-3β-ol, trimethylsilyl ether
EINECS	Contact for details

Quality Control

Our Trimethyl[(5α-Stigmastan-3β-yl)oxy]silane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can compromise product stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.