Description

Methyl 2-(Trimethylsilyl)Propionate is a versatile organosilicon compound that serves as a valuable building block and protecting group reagent in advanced organic synthesis. Its unique structure, featuring both a silyl group and an ester functionality, makes it a critical intermediate for modifying molecular properties and enabling complex chemical transformations. This high-purity reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing sterically hindered acid moieties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring silicon-containing motifs.
• Polymer & Material Science: Serves as a monomer or modifying agent for creating specialty silicones, coatings, and polymers with tailored surface properties.
• Organic Synthesis Reagent: Acts as a trimethylsilyl (TMS) protecting group for carboxylic acids or as a precursor for generating nucleophilic silyl enol ethers.
• Flavor & Fragrance Industry: Intermediate in the synthesis of certain silicon-modified ester compounds for specialty aroma chemicals.
• Chemical Research & Development: A valuable tool for methodological development in asymmetric synthesis and new bond-forming reactions in academic and industrial R&D labs.

Basic Information

Product Name	Methyl 2-(Trimethylsilyl)Propionate
CAS No.	55453-09-3
Molecular Formula	C7H16O2Si
Molecular Weight	160.29 g/mol
Synonyms	Methyl 2-(Trimethylsilyl)propanoate; 2-(Trimethylsilyl)propionic Acid Methyl Ester; Methyl Trimethylsilylpropionate; Methyl α-(Trimethylsilyl)propionate; MTPM Ester; Methyl 2-(TMS)propionate; Propanoic acid, 2-(trimethylsilyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-(Trimethylsilyl)Propionate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
Specific Gravity (20°C)	0.88 - 0.92
Refractive Index (n20D)	1.410 - 1.420

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.