Description

3β-(Trimethylsiloxy)-5α-Ergosta-8,24(28)-Diene is a high-purity, organosilicon-protected ergostane derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in enabling precise, high-yield transformations in the synthesis of complex steroidal molecules and vitamin D analogs. This compound is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers focused on steroid chemistry, novel drug discovery, and the synthesis of bioactive natural products.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of novel steroidal drugs and therapeutic agents.
• Vitamin D Analog Synthesis: Serves as a pivotal precursor in the research and production of calcitriol analogs and related secosteroids.
• Steroid Chemistry Research: Used in academic and industrial R&D for exploring new steroid transformations and reaction pathways.
• Fine Chemical Production: Employed in the manufacture of high-value, specialized chemicals for the life sciences sector.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	3β-(Trimethylsiloxy)-5α-Ergosta-8,24(28)-Diene
CAS No.	55429-71-5
Molecular Formula	C31H54OSi
Molecular Weight	470.85 g/mol
Synonyms	5α-Ergosta-8,24(28)-dien-3β-ol, 3-(trimethylsilyl) ether; Ergosta-8,24(28)-dien-3-ol, 3-(trimethylsilyl) ether, (3β,5α)-; 3β-Trimethylsiloxy-5α-ergosta-8,24(28)-diene; (3β,5α)-Ergosta-8,24(28)-dien-3-yl trimethylsilyl ether; TMS-Protected 5α-Ergosta-8,24(28)-dien-3β-ol; 3-TMS-5α-Ergosta-8,24(28)-diene
EINECS	Contact for details

Quality Control

Our 3β-(Trimethylsiloxy)-5α-Ergosta-8,24(28)-Diene is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.