Description

Trimethyl[(4α-Methyl-5α-Cholest-7-En-3β-Yl)Oxy]Silane is a high-purity organosilicon derivative of a sterol, specifically designed for advanced chemical synthesis and research. This compound is valued for its role as a versatile silylating agent and a key protected intermediate in the synthesis of complex steroid analogs and other bioactive molecules. It is primarily utilized by research institutions and pharmaceutical development companies working on novel therapeutic agents, advanced material science, and specialized fine chemical production.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel steroid-based drugs and active pharmaceutical ingredients (APIs).
• Protecting Group Chemistry: Used to protect hydroxyl groups during complex organic synthesis, enabling selective reactions in sensitive molecular frameworks.
• Bioconjugation & Labeling: Facilitates the introduction of silicon-containing tags or linkers onto sterol backbones for diagnostic or biochemical research applications.
• Material Science Research: Serves as a precursor for creating functionalized surfaces or hybrid organic-inorganic materials with specific sterol functionalities.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and compound identification.

Basic Information

Product Name	Trimethyl[(4α-Methyl-5α-Cholest-7-En-3β-Yl)Oxy]Silane
CAS No.	55429-63-5
Molecular Formula	C₃₁H₅₆OSi
Molecular Weight	472.87 g/mol
Synonyms	3β-[(Trimethylsilyl)oxy]-4α-methyl-5α-cholest-7-ene; 4α-Methyl-5α-cholest-7-en-3β-ol trimethylsilyl ether; Cholest-7-en-3-ol, 4-methyl-, 3-trimethylsilyl ether, (3β,4α,5α)-; Trimethyl(4α-methyl-5α-cholest-7-en-3β-yloxy)silane; 4-Methylcholest-7-en-3β-yloxytrimethylsilane; Silylated 4α-methylcholest-7-en-3β-ol; TMS ether of 4α-methyl-5α-cholest-7-en-3β-ol
EINECS	Contact for details

Quality Control

Our Trimethyl[(4α-Methyl-5α-Cholest-7-En-3β-Yl)Oxy]Silane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.