Description

3-[(Trimethylsilyl)Oxy]Cholest-5-En-7-One is a high-purity steroidal intermediate featuring a trimethylsilyl-protected hydroxyl group, which enhances its stability and reactivity for advanced synthetic transformations. This compound is critical for researchers and manufacturers requiring precise chemical modifications to the cholestane backbone. It serves as a key building block in the pharmaceutical and fine chemical industries, particularly for the synthesis of novel steroid derivatives and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex steroid-based drugs and hormone analogs.
• Research & Development: Used in academic and industrial R&D for exploring new synthetic pathways and creating novel steroidal compounds with potential biological activity.
• Fine Chemical Synthesis: Serves as a specialized starting material for producing high-value, custom steroidal compounds used in various chemical applications.
• Reference Standard: Can be utilized as an analytical standard for method development and quality control in steroid analysis.

Basic Information

Product Name	3-[(Trimethylsilyl)Oxy]Cholest-5-En-7-One
CAS No.	55429-58-8
Molecular Formula	C₃₀H₅₂O₂Si
Molecular Weight	472.82 g/mol
Synonyms	Cholest-5-en-7-one, 3-[(trimethylsilyl)oxy]-; 3β-[(Trimethylsilyl)oxy]cholest-5-en-7-one; 3-TMS-Oxy-cholest-5-en-7-one; 7-Oxocholest-5-en-3β-yl trimethylsilyl ether; 3β-Trimethylsiloxycholest-5-en-7-one; (3β)-3-[(Trimethylsilyl)oxy]cholest-5-en-7-one
EINECS	Contact for details

Quality Control

Our 3-[(Trimethylsilyl)Oxy]Cholest-5-En-7-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.