Description

6,7-Dimethoxy-1-Methyl-1H-Spiro[Isoquinoline-3,4-Piperidin]-4(2H)-One is a sophisticated spirocyclic organic compound that serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis. Its unique molecular architecture, featuring fused isoquinoline and piperidine rings, makes it highly valuable for constructing complex bioactive molecules. This compound is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting neurological and cardiovascular disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Alkaloid Synthesis: Serves as a building block for the synthesis of complex natural product analogs and isoquinoline-derived alkaloids.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and biological pathways.
• Organic Synthesis: Employed in advanced organic transformations to introduce spirocyclic complexity into target molecules.

Basic Information

Product Name	6,7-Dimethoxy-1-Methyl-1H-Spiro[Isoquinoline-3,4-Piperidin]-4(2H)-One
CAS No.	55423-58-0
Molecular Formula	C₁₆H₂₀N₂O₃
Molecular Weight	288.34 g/mol
Synonyms	6,7-Dimethoxy-1-methyl-1H-spiro[isoquinoline-3,4'-piperidin]-4(2H)-one; 1-Methyl-6,7-dimethoxy-1H-spiro[isoquinoline-3,4'-piperidin]-4(2H)-one; Spiro[isoquinoline-3,4'-piperidine]-4(2H)-one, 6,7-dimethoxy-1-methyl-; 6,7-Dimethoxy-1-methylspiro[isoquinoline-3,4'-piperidine]-4(2H)-one; 55423-58-0; CAS 55423-58-0
EINECS	Contact for details

Quality Control

Our production of 6,7-Dimethoxy-1-Methyl-1H-Spiro[Isoquinoline-3,4-Piperidin]-4(2H)-One adheres to stringent quality protocols suitable for pharmaceutical intermediate applications. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee batch-to-batch consistency and traceability for your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.