Description

3-O,4-O,5-o-Tris(Trimethylsilyl)-6-o-[Bis(Trimethylsilyloxy)Phosphinyl]-2-Deoxy-D-Arabino-Hexose o-Methyl Oxime CAS NO 55401-79-1 is a sophisticated, multi-functional silyl-protected carbohydrate derivative with a phosphinyl group. This compound is a critical high-purity synthetic intermediate used in the development of complex bioactive molecules, particularly in nucleoside and carbohydrate chemistry. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require precise building blocks for advanced synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel nucleoside analogs and modified sugars with potential antiviral or anticancer activity.
• Agrochemical Research: Used in creating advanced active ingredients that require specific sugar-phosphate backbone structures.
• Carbohydrate Chemistry: Serves as a protected and activated precursor for the controlled synthesis of complex oligosaccharides and glycoconjugates.
• Pro-drug Development: Utilized in designing phosphate-containing pro-drugs to enhance the bioavailability and targeting of therapeutic agents.
• Chemical Biology Probes: Acts as a substrate or inhibitor in enzymatic studies related to glycosyltransferases and kinases.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating specialty chemicals with high added value.

Basic Information

Item	Detail
Product Name	3-O,4-O,5-o-Tris(Trimethylsilyl)-6-o-[Bis(Trimethylsilyloxy)Phosphinyl]-2-Deoxy-D-Arabino-Hexose o-Methyl Oxime
CAS No.	55401-79-1
Molecular Formula	C21H52N1O8P1Si5
Molecular Weight	Approx. 638.1 g/mol
Synonyms	6-O-[Bis(trimethylsilyloxy)phosphinyl]-2-deoxy-3,4,5-O-tris(trimethylsilyl)-D-arabino-hexose O-methyloxime; 2-Deoxy-3,4,5-O-tris(trimethylsilyl)-6-O-[bis(trimethylsilyloxy)phosphinyl]-D-arabino-hexose O-methyloxime; TMS-Protected Phosphinyl Hexose Methyl Oxime; Silylated Phosphorylated Sugar Oxime; 55401-79-1; Per-TMS Phosphinyl Sugar Derivative
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and tested under strict quality control protocols to ensure consistency and purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by HPLC/NMR), identity, and moisture content. Our quality system is designed to support cGMP and ISO standards for traceability and reliability in research and development supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions, preferably in a glovebox or under an inert atmosphere (argon/nitrogen) when opening the primary container to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.