Description

1-O,3-o-Diacetyl-2-o-Oleoylglycerol is a structured triglyceride, specifically a diacetin ester of oleic acid, which serves as a versatile intermediate and functional ingredient. This compound is valued for its unique molecular architecture, offering specific lipophilicity and reactivity that can be tailored for advanced synthesis. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, nutraceutical, and specialty chemical industries for developing novel drug delivery systems, lipid-based formulations, and high-value biochemicals.

Application

• Pharmaceutical Intermediate: Used in the research and synthesis of prodrugs and active pharmaceutical ingredients (APIs) requiring specific lipid conjugation.
• Lipid Excipient Development: Serves as a model compound or functional component in formulating advanced lipid-based drug delivery systems (e.g., self-emulsifying drug delivery systems - SEDDS).
• Biochemical Research: Acts as a substrate or standard in enzymatic studies, particularly those involving lipases and esterases, to understand lipid metabolism.
• Specialty Surfactant & Emulsifier Synthesis: Provides a backbone for creating novel non-ionic surfactants with tailored hydrophilic-lipophilic balance (HLB) properties.
• Nutraceutical Formulations: Investigated for use in structured lipid preparations designed for targeted nutritional or medical food applications.
• Organic Synthesis Building Block: Utilized as a chiral synthon or protected glycerol derivative in complex multi-step organic syntheses.

Basic Information

Product Name	1-O,3-o-Diacetyl-2-o-Oleoylglycerol
CAS No.	55401-63-3
Molecular Formula	C25H44O6
Molecular Weight	440.62 g/mol
Synonyms	1,3-Diacetin-2-oleate; 1,3-Diacetyl-2-oleoylglycerol; 2-Oleoyl-1,3-diacetylglycerol; Diolein diacetate (mixed isomer); Glycerol 1,3-diacetate 2-oleate; TAG 18:1/2:0/2:0 (structured); 1,3-Di-O-acetyl-2-O-oleoylglycerol; Oleic acid diester with glycerol diacetate
EINECS	Contact for details

Quality Control

Our 1-O,3-o-Diacetyl-2-o-Oleoylglycerol is produced and controlled under a strict quality management system. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed batch-specific results are available upon request. We support development projects by providing material that meets in-house specifications aligned with cGMP and ISO 9001 principles for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This material is easily oxidized; prolonged exposure to air or elevated temperatures should be avoided to maintain stability. Keep the container in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Acid Value	≤ 1.0 mg KOH/g
Peroxide Value	≤ 5.0 meq/kg
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.