Description

4-Bromobenzimidic Acid Ethyl Ester Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial importance. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry and advanced material science. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel benzimidazole-derived drug candidates, including potential antivirals, antifungals, and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the benzimidazole scaffold.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, to introduce functionalized aromatic systems into more complex structures.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology & Proteomics: Utilized as a reagent for modifying peptides or proteins, or in the synthesis of chemical probes for target identification and validation.

Basic Information

Product Name	4-Bromobenzimidic Acid Ethyl Ester Hydrochloride
CAS No.	55368-83-7
Molecular Formula	C9H9BrClNO2 • HCl
Molecular Weight	308.54 g/mol (Free base: 272.53 g/mol)
Synonyms	Ethyl 4-Bromobenzimidate Hydrochloride; 4-Bromo-Benzenecarboximidic Acid Ethyl Ester Hydrochloride; Benzenecarboximidic acid, 4-bromo-, ethyl ester, hydrochloride; Ethyl (4-bromophenyl)imidate hydrochloride; 4-Bromophenyl imidoic acid ethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Bromobenzimidic Acid Ethyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for pharmaceutical-grade intermediates, ensuring traceability and documentation for regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.