Description

4-(3-Methyl-2-Butenyl)-Nα-(Trifluoroacetyl)-L-Tryptophan Methyl Ester is a sophisticated, high-purity synthetic intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex molecules, particularly in pharmaceutical research and peptide chemistry. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating novel therapeutic agents and bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Peptide Synthesis: Used as a protected tryptophan derivative in solid-phase and solution-phase peptide synthesis to construct complex peptide sequences.
• Bioconjugation & Probe Development: Serves as a starting material for creating fluorescent probes, affinity labels, or other bioconjugates for biochemical research.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize the biological activity of new chemical entities.
• Process Chemistry & Scale-up: Used in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: A valuable reagent for universities and research institutes conducting studies in organic synthesis and chemical biology.

Basic Information

Product Name	4-(3-Methyl-2-Butenyl)-Nα-(Trifluoroacetyl)-L-Tryptophan Methyl Ester
CAS No.	55334-65-1
Molecular Formula	C19H21F3N2O3
Molecular Weight	382.38 g/mol
Synonyms	N-[(Trifluoroacetyl)-L-tryptophan]-3,3-dimethylallyl ester; L-Tryptophan, 4-(3-methyl-2-buten-1-yl)-N-(trifluoroacetyl)-, methyl ester; Nα-Trifluoroacetyl-4-(3-methyl-2-butenyl)-L-tryptophan methyl ester; 4-Prenyl-Nα-TFA-L-tryptophan methyl ester; Fmoc-Tryptophan(Prenyl)-OH precursor; Tryptophan derivative with prenyl and TFA protecting groups; Methyl (2S)-2-[(2,2,2-trifluoroacetyl)amino]-3-[4-[(3-methylbut-2-en-1-yl)]-1H-indol-3-yl]propanoate
EINECS	Contact for details

Quality Control

Our 4-(3-Methyl-2-Butenyl)-Nα-(Trifluoroacetyl)-L-Tryptophan Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and comprehensive identification tests. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, ensuring compliance with the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be sensitive to moisture; therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (L-Isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.