Description

3α,7α-Bis[(Trimethylsilyl)Oxy]-5β-Cholan-24-Oic Acid Trimethylsilyl Ester is a key protected derivative of cholanic acid, specifically designed for advanced synthetic chemistry. This compound is critically important as a versatile synthetic intermediate, offering enhanced stability and solubility for precise derivatization reactions. It is primarily utilized by research institutions and pharmaceutical developers in the synthesis of complex steroid analogs, bile acid derivatives, and other high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel steroid-based therapeutics and diagnostic agents.
• Biochemical Research: Used in metabolic pathway studies and as a protected precursor for generating labeled bile acid analogs for tracer studies.
• Fine Chemical Synthesis: Serves as a protected intermediate for the production of specialized cholic acid derivatives with tailored properties.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Material Science: Potential precursor for synthesizing specialized surfactants or liquid crystal components due to its steroidal backbone.

Basic Information

Product Name	3α,7α-Bis[(Trimethylsilyl)Oxy]-5β-Cholan-24-Oic Acid Trimethylsilyl Ester
CAS No.	55320-14-4
Molecular Formula	C32H60O4Si3
Molecular Weight	593.07 g/mol
Synonyms	3α,7α-Bis(trimethylsiloxy)-5β-cholan-24-oic Acid Trimethylsilyl Ester; 5β-Cholan-24-oic Acid, 3α,7α-bis[(trimethylsilyl)oxy]-, Trimethylsilyl Ester; Trimethylsilyl 3α,7α-Bis(trimethylsiloxy)-5β-cholan-24-oate; TMS Derivative of Cholic Acid; Protected Cholic Acid TMS Ester; 3α,7α-Di-O-TMS-5β-cholan-24-oic Acid TMS Ester
EINECS	Contact for details

Quality Control

Our 3α,7α-Bis[(Trimethylsilyl)Oxy]-5β-Cholan-24-Oic Acid Trimethylsilyl Ester is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to support our global clientele in pharmaceutical and fine chemical sectors.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.