Description

1,3-Bis[(Trimethylsilyl)Oxy]Cyclohexane CAS NO 55320-10-0 is a specialized organosilicon compound featuring a cyclohexane backbone protected by trimethylsilyl (TMS) ether groups. This compound serves as a valuable protected intermediate and silylating agent in advanced organic synthesis, offering enhanced stability and reactivity control for sensitive transformations. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Protecting Group Chemistry: Used to protect hydroxyl groups on the cyclohexane diol moiety during complex synthetic sequences, allowing for selective reactions at other sites.
• Silylation Agent: Functions as a reagent for introducing trimethylsilyl groups into other molecules, modifying their solubility, volatility, or stability for analysis or further synthesis.
• Organic Synthesis Reagent: Employed in research and development for constructing stereochemically defined cyclic structures in natural product synthesis and material science.
• Material Science Precursor: Potential starting material for the development of silicon-containing hybrid polymers or surface modification agents.

Basic Information

Product Name	1,3-Bis[(Trimethylsilyl)Oxy]Cyclohexane
CAS No.	55320-10-0
Molecular Formula	C12H28O2Si2
Molecular Weight	260.52 g/mol
Synonyms	Cyclohexane-1,3-diol bis(trimethylsilyl) ether; 1,3-Cyclohexanediol, bis(trimethylsilyl) ether; 1,3-Bis(trimethylsiloxy)cyclohexane; 1,3-Bis(O-trimethylsilyl)cyclohexane; 1,3-Di-O-trimethylsilyl-cyclohexane-1,3-diol; TMS-protected 1,3-cyclohexanediol
EINECS	Contact for details

Quality Control

Our 1,3-Bis[(Trimethylsilyl)Oxy]Cyclohexane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment. We adhere to relevant industry standards for fine chemicals, and specifications can be aligned with customer-specific requirements for research or cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC or HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.