Description

4,8-Bis[(Trimethylsilyl)Oxy]Quinoline-2-Carboxylic Acid Trimethylsilyl Ester is a key protected intermediate in advanced organic synthesis, valued for its role in constructing complex heterocyclic frameworks. Its primary commercial importance lies in serving as a versatile building block for the development of active pharmaceutical ingredients (APIs) and specialty fine chemicals. This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking high-purity synthetic precursors.

Application

• Pharmaceutical Intermediate: A crucial protected precursor in the multi-step synthesis of quinoline-based drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides that utilize functionalized quinoline structures.
• Organic Light-Emitting Diodes (OLEDs): Serves as a starting material for synthesizing electron-transport or emissive layer components in advanced display technologies.
• Coordination Chemistry & Ligand Design: The functional groups can be deprotected to create novel chelating ligands for catalytic and material science applications.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and heterocyclic chemistry research.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and complex organic molecules requiring specific quinoline motifs.

Basic Information

Product Name	4,8-Bis[(Trimethylsilyl)Oxy]Quinoline-2-Carboxylic Acid Trimethylsilyl Ester
CAS No.	55319-89-6
Molecular Formula	C₂₂H₃₅NO₄Si₃
Molecular Weight	485.78 g/mol
Synonyms	2-Quinolinecarboxylic acid, 4,8-bis[(trimethylsilyl)oxy]-, trimethylsilyl ester; 4,8-Bis(trimethylsiloxy)quinoline-2-carboxylic acid trimethylsilyl ester; Quinoline-2-carboxylic acid, 4,8-bis(trimethylsiloxy)-, trimethylsilyl ester; TMS-protected 4,8-dihydroxyquinoline-2-carboxylate; 55319-89-6
EINECS	Contact for details

Quality Control

Our 4,8-Bis[(Trimethylsilyl)Oxy]Quinoline-2-Carboxylic Acid Trimethylsilyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent batch-to-batch reliability. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.