Description

1-O,3-O,4-o-Tris(Trimethylsilyl)-5-o-[Bis(Trimethylsilyloxy)Phosphinyl]-D-Erythro-2-Pentulose o-Methyl Oxime is a highly specialized, protected carbohydrate derivative used as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its role in constructing complex molecular architectures, particularly in nucleoside and carbohydrate chemistry, where precise stereochemistry and functional group protection are paramount. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostic agents, and fine chemicals.

Application

• Advanced Pharmaceutical Intermediates: Serves as a key building block in the synthesis of novel nucleoside analogs and modified sugars for antiviral and anticancer drug candidates.
• Carbohydrate Chemistry Research: Used in academic and industrial R&D for studying glycosylation reactions and synthesizing complex oligosaccharides with defined stereochemistry.
• Pro-drug Synthesis: Employed in the design and synthesis of phosphate or phosphonate-based pro-drugs to enhance bioavailability and targeting.
• Chemical Biology Tools: Acts as a precursor for labeled or modified sugars used in metabolic pathway studies and probe development.
• Fine Chemical Production: Utilized in the multi-step synthesis of high-value, chiral specialty chemicals for various industrial applications.

Basic Information

Product Name	1-O,3-O,4-o-Tris(Trimethylsilyl)-5-o-[Bis(Trimethylsilyloxy)Phosphinyl]-D-Erythro-2-Pentulose o-Methyl Oxime
CAS No.	55319-73-8
Molecular Formula	C20H52N1O7P1Si5
Molecular Weight	610.15 g/mol
Synonyms	D-Erythro-2-Pentulose, 1-O,3-O,4-o-tris(trimethylsilyl)-5-o-[bis(trimethylsilyloxy)phosphinyl]-, o-methyloxime; 5-O-[Bis(trimethylsilyloxy)phosphinyl]-1,3,4-tri-O-trimethylsilyl-D-erythro-2-pentulose O-methyloxime; Protected D-Erythro-2-Pentulose O-Methyl Oxime Phosphonate; TMS-Protected Pentulose Oxime Phosphonate Ester; CAS 55319-73-8
EINECS	Contact for details

Quality Control

Every batch of 1-O,3-O,4-o-Tris(Trimethylsilyl)-5-o-[Bis(Trimethylsilyloxy)Phosphinyl]-D-Erythro-2-Pentulose o-Methyl Oxime is manufactured and tested under strict quality management protocols to ensure high purity, identity, and consistency. Our quality assurance includes comprehensive analytical characterization using techniques such as NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and relevant research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.