Description

2-Hydroxy-3-(4-Methoxy-Phenyl)-Propionic Acid Ethyl Ester is a high-purity organic ester compound valued for its role as a versatile chiral building block and synthetic intermediate. Its molecular structure, featuring both a hydroxyl and an ester functional group on a propanoid backbone attached to a methoxyphenyl ring, makes it a critical precursor in sophisticated organic synthesis. This compound is essential for research and development chemists and manufacturers in the pharmaceutical and fine chemical industries, particularly for constructing complex molecules with specific stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting cardiovascular and central nervous system disorders.
• Fine Chemical Synthesis: Used in the production of advanced fragrances, flavors, and specialty agrochemicals requiring high stereochemical purity.
• Liquid Crystal & OLED Material Research: Serves as a precursor for novel organic electronic materials due to its aromatic and ester functionalities.
• Asymmetric Catalysis & Ligand Development: Employed in the development of chiral ligands and catalysts for enantioselective reactions.
• Academic & Industrial R&D: A valuable compound for methodological development in organic chemistry and process chemistry optimization.

Basic Information

Product Name	2-Hydroxy-3-(4-Methoxy-Phenyl)-Propionic Acid Ethyl Ester
CAS No.	55301-58-1
Molecular Formula	C₁₂H₁₆O₄
Molecular Weight	224.25 g/mol
Synonyms	Ethyl 2-Hydroxy-3-(4-methoxyphenyl)propanoate; Ethyl 3-(4-Methoxyphenyl)-2-hydroxypropionate; 2-Hydroxy-3-(p-methoxyphenyl)propionic Acid Ethyl Ester; (R/S)-Ethyl 2-Hydroxy-3-(4-methoxyphenyl)propionate; 4-Methoxybenzeneacetic acid, α-hydroxy-, ethyl ester; Ethyl DL-2-Hydroxy-3-(4-methoxyphenyl)propionate
EINECS	Contact for details

Quality Control

Our production of 2-Hydroxy-3-(4-Methoxy-Phenyl)-Propionic Acid Ethyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the exacting standards required for pharmaceutical and advanced synthetic applications. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (HPLC/GC), enantiomeric excess, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	Specify grade (e.g., Racemic, ≥99% ee)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.