Description

Pivoxazepam is a benzodiazepine derivative of significant interest in pharmaceutical research and development. This compound serves as a key intermediate or reference standard for the synthesis and analytical study of novel therapeutic agents targeting the central nervous system. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of anxiolytic and sedative-hypnotic medications.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of advanced benzodiazepine-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of related drug substances and products via HPLC, GC, or LC-MS.
• Biochemical Research: Employed in preclinical studies to investigate the structure-activity relationships (SAR) of ligands at the GABA-A receptor complex.
• Process Development: Serves as a model compound for optimizing chemical synthesis routes, including catalysis and purification techniques, in fine chemical production.
• Metabolite Studies: Used in the identification and characterization of metabolic pathways for related benzodiazepine drugs.

Basic Information

Product Name	Pivoxazepam
CAS No.	55299-10-0
Molecular Formula	C19H17ClN2O3
Molecular Weight	356.80 g/mol
Synonyms	7-Chloro-1,3-dihydro-5-phenyl-1-(2,2,2-trifluoroethyl)-2H-1,4-benzodiazepin-2-one 4-Oxide; Pivoxazepam; 55299-10-0; 7-Chloro-5-phenyl-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one 4-oxide; 1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-phenyl-1-(2,2,2-trifluoroethyl)-, 4-oxide
EINECS	Contact for details

Quality Control

Our Pivoxazepam is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and control of specified impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.