Description

4-Amino-3-Chloro-2-Hydroxypyridine is a versatile heterocyclic building block of significant importance in advanced organic synthesis. This compound is valued for its multifunctional structure, which allows for selective modifications to create complex molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging its pyridine core for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of high-performance, color-fast dyes and organic pigments.
• Material Science Research: Employed in the creation of organic electronic materials and metal-organic frameworks (MOFs).
• Bioconjugation Chemistry: Its amino and hydroxyl groups make it useful for creating linkers in antibody-drug conjugates (ADCs) and other bioconjugates.

Basic Information

Item	Detail
Product Name	4-Amino-3-Chloro-2-Hydroxypyridine
CAS No.	55290-73-8
Molecular Formula	C5H5ClN2O
Molecular Weight	144.56 g/mol
Synonyms	3-Chloro-2-hydroxy-4-aminopyridine; 4-Amino-3-chloro-2(1H)-pyridinone; 2-Hydroxy-4-amino-3-chloropyridine; 3-Chloro-4-amino-2-pyridinol; 4-Amino-3-chloro-2-pyridone; 3-Chloro-4-aminopyridin-2-ol; 2-Pyridinol, 4-amino-3-chloro-
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Chloro-2-Hydroxypyridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) documenting all critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.