Description

1,2,3,6-Tetra-o-Acetyl-α-D-Glucopyranose is a key acetylated sugar derivative, serving as a vital protected intermediate in sophisticated organic synthesis. Its primary value lies in enabling the selective manipulation of carbohydrate molecules, which is essential for producing complex bioactive compounds. This high-purity building block is indispensable for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, particularly for developing nucleoside analogs, glycoconjugates, and other advanced therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial protected synthon for the synthesis of nucleoside analogs, antiviral drugs, and other carbohydrate-based active pharmaceutical ingredients (APIs).
• Glycochemistry Research: Used as a starting material or intermediate in the study and synthesis of complex oligosaccharides, glycopeptides, and glycolipids.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, chiral auxiliaries, and advanced materials requiring specific sugar scaffolds.
• Bioconjugation: Acts as a precursor for creating linkers and modified sugars used in antibody-drug conjugates (ADCs) and other bioconjugation strategies.
• Process Development: Serves as a reference standard and a key raw material in the scale-up and process optimization for carbohydrate chemistry.

Basic Information

Product Name	1,2,3,6-Tetra-o-Acetyl-α-D-Glucopyranose
CAS No.	55286-97-0
Molecular Formula	C14H20O10
Molecular Weight	348.30 g/mol
Synonyms	α-D-Glucopyranose, 1,2,3,6-tetraacetate; 1,2,3,6-Tetra-O-acetyl-α-D-glucopyranose; α-D-Glucose Tetraacetate; Tetra-O-acetyl-α-D-glucopyranose; 1,2,3,6-Tetra-O-acetyl-α-D-glucose; α-Acetoglucal (historical); α-D-Glucopyranosyl Tetraacetate
EINECS	Contact for details

Quality Control

Our 1,2,3,6-Tetra-o-Acetyl-α-D-Glucopyranose is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support regulatory filings with appropriate documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent hydrolysis of the acetyl groups.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	[α]20/D: +100° to +110° (c=1 in CHCl3)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.