Description

Methyl 3-(Acetylamino)-2-O,4-O,6-o-Tris(Trimethylsilyl)-3-Deoxy-α-D-Glucopyranoside is a key protected carbohydrate derivative, specifically a fully silylated and acetylated methyl glucoside, essential for advanced synthetic organic chemistry. Its value lies in its role as a versatile and stable synthetic intermediate, where the trimethylsilyl (TMS) protecting groups allow for selective deprotection and further functionalization at specific hydroxyl positions. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex glycoconjugates, nucleoside analogs, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel glycosylated drugs, antiviral agents, and antibiotic derivatives.
• Glycochemistry Research: Used in academic and industrial R&D for studying glycosylation reactions, carbohydrate-protein interactions, and enzyme mechanisms.
• Nucleoside Analog Synthesis: Serves as a protected sugar moiety for the preparation of modified nucleosides with potential therapeutic applications.
• Fine Chemical Production: Employed in multi-step syntheses to create complex, high-value specialty chemicals and chiral auxiliaries.
• Agrochemical Development: Acts as an intermediate in the creation of new, more effective crop protection agents with specific modes of action.
• Protecting Group Strategy: Demonstrates the utility of silyl ethers in complex molecule assembly, allowing for orthogonal deprotection sequences.

Basic Information

Product Name	Methyl 3-(Acetylamino)-2-O,4-O,6-o-Tris(Trimethylsilyl)-3-Deoxy-α-D-Glucopyranoside
CAS No.	55282-23-0
Molecular Formula	C20H45NO6Si3
Molecular Weight	503.82 g/mol
Synonyms	Methyl 3-Acetamido-2,4,6-tri-O-trimethylsilyl-3-deoxy-α-D-glucopyranoside; 3-Acetamido-3-deoxy-2,4,6-tri-O-(trimethylsilyl)-α-D-glucopyranoside methyl glycoside; Methyl 3-acetamido-3-deoxy-2,4,6-tri-O-trimethylsilyl-α-D-glucopyranoside; TMS-protected Methyl N-Acetyl-α-D-glucosaminide; 1-O-Methyl-3-acetamido-3-deoxy-2,4,6-tri-O-trimethylsilyl-α-D-glucopyranoside
EINECS	Contact for details

Quality Control

Our Methyl 3-(Acetylamino)-2-O,4-O,6-o-Tris(Trimethylsilyl)-3-Deoxy-α-D-Glucopyranoside is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.