Description

3-[Bis(Trimethylsilyl)Amino]-2-(Trimethylsilylamino)Propionic Acid Trimethylsilyl Ester is a highly functionalized, multi-silylated organic compound primarily used as a key synthetic intermediate and protecting group reagent. Its value lies in its ability to introduce multiple trimethylsilyl (TMS) groups, which are crucial for modifying reactivity and solubility in complex organic syntheses. This specialty chemical is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors, where precise molecular construction is required.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex drug molecules, particularly those requiring silyl-protected amino acid derivatives.
• Peptide Synthesis: Used as a specialized reagent for the protection of amino and carboxylic acid groups during solid-phase and solution-phase peptide synthesis.
• Organosilicon Chemistry: Acts as a versatile precursor for the preparation of novel organosilicon compounds and functionalized silanes.
• Material Science Research: Employed in the development of advanced polymeric materials and surface modifiers where silyl groups impart specific properties.
• Agrochemical Synthesis: Utilized as an intermediate in the research and development of new active ingredients that benefit from silylated intermediates.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	3-[Bis(Trimethylsilyl)Amino]-2-(Trimethylsilylamino)Propionic Acid Trimethylsilyl Ester
CAS No.	55281-99-7
Molecular Formula	C15H39N2O2Si3
Molecular Weight	377.75 g/mol
Synonyms	3-[Bis(trimethylsilyl)amino]-2-(trimethylsilylamino)propionic acid trimethylsilyl ester; 2,3-Bis(trimethylsilylamino)propionic Acid Trimethylsilyl Ester; N,N-Bis(trimethylsilyl)-3-[(trimethylsilyl)amino]-L-alanine Trimethylsilyl Ester; Propanoic acid, 3-[bis(trimethylsilyl)amino]-2-[(trimethylsilyl)amino]-, trimethylsilyl ester; TMS-Protected β-Amino Alanine Derivative
EINECS	Contact for details

Quality Control

Our production of 3-[Bis(Trimethylsilyl)Amino]-2-(Trimethylsilylamino)Propionic Acid Trimethylsilyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and industrial use. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) documenting all critical specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.