Description

α,3,4-Tris(Trimethylsiloxy)Benzeneacetic Acid Methyl Ester is a specialized organosilicon compound featuring a unique aromatic core modified with multiple trimethylsiloxy groups. This structure makes it a valuable protected intermediate and functional building block in advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecules where selective deprotection and further functionalization are required.

Application

• Pharmaceutical Intermediate: Serves as a key protected synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly those with complex phenolic or carboxylic acid functionalities.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators where its siloxy groups provide temporary protection during synthesis.
• Advanced Material Precursor: Acts as a monomer or modifying agent in the synthesis of specialty silicones, silicone-aryl hybrid polymers, and other performance materials.
• Organic Synthesis Building Block: Employed in academic and industrial research laboratories for constructing complex aromatic compounds, leveraging the trimethylsiloxy groups for regioselective reactions.
• Liquid Crystal and OLED Material Research: Investigated as a potential intermediate for creating novel organic semiconductors and liquid crystal molecules due to its modified aromatic structure.

Basic Information

Product Name	α,3,4-Tris(Trimethylsiloxy)Benzeneacetic Acid Methyl Ester
CAS No.	55268-65-0
Molecular Formula	C19H34O5Si3
Molecular Weight	426.73 g/mol
Synonyms	Methyl 2-[3,4-bis(trimethylsilyloxy)phenyl]-2-(trimethylsilyloxy)acetate; Methyl α,3,4-tris(trimethylsiloxy)benzeneacetate; Benzeneacetic acid, α,3,4-tris(trimethylsiloxy)-, methyl ester; 2-[3,4-Bis(trimethylsilyloxy)phenyl]-2-(trimethylsilyloxy)acetic acid methyl ester; TMS-protected methyl dihydroxyphenylglyoxylate derivative
EINECS	Contact for details

Quality Control

Our production of α,3,4-Tris(Trimethylsiloxy)Benzeneacetic Acid Methyl Ester adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is characterized using advanced analytical techniques including NMR, HPLC, and GC to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.