Description

1-(Trimethylsilyl)-2-Piperidinecarboxylic Acid Trimethylsilyl Ester is a high-purity, organosilicon-protected derivative of pipecolic acid, designed for advanced synthetic applications. This compound is valued for its role as a key protected intermediate in organic synthesis, offering enhanced stability and reactivity control. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules and active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those containing piperidine or modified amino acid motifs.
• Peptidomimetic Research: Used to introduce sterically hindered, silyl-protected amino acid analogs into peptide chains to study structure-activity relationships.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced crop protection agents with specific biological activity.
• Ligand and Catalyst Development: Employed in the preparation of specialized chiral ligands or organocatalysts for asymmetric synthesis.
• Material Science Precursor: Can be utilized in the synthesis of silicon-containing polymers or hybrid organic-inorganic materials.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic pathways.

Basic Information

Product Name	1-(Trimethylsilyl)-2-Piperidinecarboxylic Acid Trimethylsilyl Ester
CAS No.	55255-44-2
Molecular Formula	C12H25NO2Si2
Molecular Weight	259.51 g/mol
Synonyms	2-(Trimethylsilyloxycarbonyl)-1-(trimethylsilyl)piperidine; 1-Trimethylsilyl-2-piperidinecarboxylic Acid Trimethylsilyl Ester; 2-Piperidinecarboxylic Acid, 1-(Trimethylsilyl)-, Trimethylsilyl Ester; Silylated Pipecolic Acid Ester; N,O-Bis(trimethylsilyl)pipecolate; Protected Pipecolic Acid Derivative; TMS-Pipecolic Acid TMS Ester
EINECS	Contact for details

Quality Control

Our production of 1-(Trimethylsilyl)-2-Piperidinecarboxylic Acid Trimethylsilyl Ester adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.