Description

1-(2,2-Dichloro-1,1-Difluoroethoxy)-4-Isocyanatobenzene is a specialized aromatic isocyanate derivative containing a halogenated ethoxy substituent. This compound is a critical building block in advanced polymer synthesis, valued for its ability to introduce both isocyanate functionality and halogenated segments into a molecular backbone. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical and high-performance materials sectors for creating novel polymers, coatings, and bioactive intermediates with tailored properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic motifs for bioactivity or metabolic stability.
• Polyurethane & Polyurea Synthesis: Serves as a reactive monomer for producing specialty polyurethanes and polyureas with enhanced chemical resistance, flame retardancy, and weatherability due to the halogen content.
• Advanced Material Crosslinker: Used to crosslink polymers in high-performance coatings, adhesives, and elastomers, improving thermal stability and mechanical strength.
• Agrochemical Synthesis: Intermediate in the development of novel herbicides, fungicides, and insecticides where the difluorodichloroethoxy group imparts specific biological activity.
• Liquid Crystal & OLED Materials: Building block for synthesizing halogenated aromatic components used in electronic display and lighting materials.
• Surface Modification Agent: Employed to functionalize surfaces with isocyanate groups for subsequent covalent attachment of biomolecules or other functional layers.

Basic Information

Product Name	1-(2,2-Dichloro-1,1-Difluoroethoxy)-4-Isocyanatobenzene
CAS No.	55225-96-2
Molecular Formula	C9H5Cl2F2NO2
Molecular Weight	280.05 g/mol
Synonyms	4-Isocyanato-1-(2,2-dichloro-1,1-difluoroethoxy)benzene; p-Isocyanatophenol 2,2-dichloro-1,1-difluoroethyl ether; 2,2-Dichloro-1,1-difluoroethyl p-isocyanatophenyl ether; Benzene, 1-(2,2-dichloro-1,1-difluoroethoxy)-4-isocyanato-; 4-(2,2-Dichloro-1,1-difluoroethoxy)phenyl isocyanate
EINECS	Contact for details

Quality Control

Our production of 1-(2,2-Dichloro-1,1-Difluoroethoxy)-4-Isocyanatobenzene adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting compliance in regulated research and manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept sealed under a dry inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis of the isocyanate group. Keep away from heat, sparks, open flames, and incompatible materials such as alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Free Isocyanate (NCO) Content	Contact for details
Density (at 20°C)	~1.5 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.