Description

(10α)-6α-Methylpregn-4-Ene-3,20-Dione CAS NO 55220-88-7 is a high-purity synthetic steroid intermediate of significant commercial and research importance. This compound serves as a critical building block in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical manufacturers and advanced research institutions engaged in steroid chemistry and drug development.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of steroidal drugs, including certain corticosteroids and progestogens.
• Research & Development: Used in academic and industrial laboratories for studying steroid metabolism, receptor binding, and structure-activity relationships (SAR).
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control testing in pharmaceutical analysis.
• Process Chemistry: Employed in the development and optimization of novel synthetic pathways for steroid production at pilot and commercial scales.

Basic Information

Product Name	(10α)-6α-Methylpregn-4-Ene-3,20-Dione
CAS No.	55220-88-7
Molecular Formula	C22H32O2
Molecular Weight	328.49 g/mol
Synonyms	6α-Methyl-4-pregnene-3,20-dione; 6α-Methylprogesterone; 6α-Methyl-4-pregnene-3,20-dione; 6α-Methylpregn-4-ene-3,20-dione; 6α-Methyl-δ4-pregnene-3,20-dione; 6α-Methyl-4-pregnene-3,20-dione (10α); 6α-Methyl-10α-pregn-4-ene-3,20-dione
EINECS	Contact for details

Quality Control

Our (10α)-6α-Methylpregn-4-Ene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards suitable for pharmaceutical R&D and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.