Description

n-(Trifluoroacetyl)-L-Val-Gly-L-Ala-Ome is a specialized, high-purity tripeptide derivative designed for advanced research and development applications. This compound is a critical building block in the synthesis of complex peptides and peptidomimetics, offering precise structural control. It is primarily utilized by pharmaceutical researchers, biochemists, and fine chemical manufacturers engaged in drug discovery, proteomics, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Protease Substrate Analog: Used in biochemical research to study enzyme kinetics, specificity, and inhibition mechanisms of proteolytic enzymes.
• Peptidomimetic Synthesis: Acts as a core scaffold for creating modified peptides with enhanced stability, bioavailability, or biological activity.
• Solid-Phase Peptide Synthesis (SPPS): Employed as a protected amino acid sequence in automated peptide synthesizers for constructing longer peptide chains.
• Bioconjugation & Labeling Studies: The trifluoroacetyl group provides a handle for further chemical modification and conjugation in biophysical studies.
• Academic & Industrial R&D: Essential for research in medicinal chemistry, structural biology, and the exploration of new bioactive compounds.

Basic Information

Product Name	n-(Trifluoroacetyl)-L-Val-Gly-L-Ala-Ome
CAS No.	55191-31-6
Molecular Formula	C15H22F3N3O6
Molecular Weight	397.35 g/mol
Synonyms	N-(Trifluoroacetyl)-L-valylglycyl-L-alanine methyl ester; N-TFA-L-Val-Gly-L-Ala-OMe; L-Valine, N-[(trifluoroacetyl)glycyl-L-alanine] methyl ester; Methyl N-(trifluoroacetyl)-L-valylglycyl-L-alaninate; TFA-Val-Gly-Ala-OMe; (S)-Methyl 2-((S)-2-((S)-2-((2,2,2-trifluoroacetyl)amino)-3-methylbutanamido)acetamido)propanoate; N-(Trifluoroacetyl)valylglycylalanine methyl ester
EINECS	Contact for details

Quality Control

Our n-(Trifluoroacetyl)-L-Val-Gly-L-Ala-Ome is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. We provide comprehensive analytical data, including HPLC purity, chiral purity, and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is available with every shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is moisture-sensitive (hygroscopic) and should be handled under anhydrous conditions when possible to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.