Description

2-O,3-O,4-O,5-o-Tetrakis(Trimethylsilyl)-6-o-[2-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-α-D-Glucopyranosyl]-D-Glucose is a highly functionalized, fully protected disaccharide derivative, serving as a critical advanced intermediate in complex organic synthesis. Its value lies in providing a precisely defined, multi-silylated scaffold that enables selective deprotection strategies for constructing sophisticated carbohydrate-based molecules. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel glycoconjugates, prodrugs, and bioactive oligosaccharides where precise stereochemistry and protection group chemistry are paramount.

Application

• Advanced Pharmaceutical Intermediates: Key building block for the synthesis of complex carbohydrate-based active pharmaceutical ingredients (APIs) and prodrugs.
• Glycoconjugate Synthesis: Used in the development of vaccines, diagnostic agents, and targeted therapeutics that rely on specific carbohydrate motifs.
• Oligosaccharide and Glycan Assembly: Serves as a protected donor or acceptor in glycosylation reactions for constructing defined oligosaccharide chains.
• Chemical Biology Research: Tool compound for studying carbohydrate-protein interactions, enzyme mechanisms, and metabolic pathways.
• Specialty Chemical Synthesis: Intermediate for creating surfactants, ligands, or chiral auxiliaries with tailored solubility and reactivity profiles.
• Standards and Reference Materials: High-purity material for use as an analytical standard in chromatography and spectrometry for quality control in carbohydrate chemistry.

Basic Information

Product Name	2-O,3-O,4-O,5-o-Tetrakis(Trimethylsilyl)-6-o-[2-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-α-D-Glucopyranosyl]-D-Glucose
CAS No.	55191-01-0
Molecular Formula	C42H96O11Si8
Molecular Weight	1025.96 g/mol
Synonyms	Per-O-trimethylsilyl maltose (fully protected); 1,2,3,4,6-Penta-O-trimethylsilyl-α-D-glucopyranosyl-(1→4)-1,2,3,6-tetra-O-trimethylsilyl-D-glucopyranose; Fully silylated maltose; Octakis(trimethylsilyl) maltose; α-D-Glucopyranosyl-(1→4)-D-glucopyranose, octakis-O-(trimethylsilyl) derivative; Maltose, octakis(trimethylsilyl) ether; TMS-maltose (fully protected)
EINECS	Contact for details

Quality Control

Our production of this advanced synthetic intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high chemical purity. Identity and purity are confirmed through a combination of advanced analytical techniques including NMR (¹H, ¹³C), HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, supporting its use in GMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to prevent decomposition. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.