Description

n-(Trifluoroacetyl)-β-Alanine (S)-1-Methylpropyl Ester is a high-purity chiral building block and synthetic intermediate of significant commercial interest. Its value lies in the trifluoroacetyl protecting group and the defined stereochemistry of the (S)-1-methylpropyl ester moiety, which are critical for directing subsequent reactions and achieving desired biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients, peptide mimetics, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel active pharmaceutical ingredients (APIs), especially for protease inhibitors and other targeted therapies.
• Peptidomimetic Chemistry: Used to introduce the trifluoroacetyl-protected β-alanine moiety into peptide backbones, modifying stability, lipophilicity, and metabolic resistance.
• Agrochemical Synthesis: Serves as a building block for creating advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals where fluorine incorporation enhances thermal and chemical stability.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes and molecular tags for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring high stereochemical purity and reliable scalability.

Basic Information

Item	Details
Product Name	n-(Trifluoroacetyl)-β-Alanine (S)-1-Methylpropyl Ester
CAS No.	55133-79-4
Molecular Formula	C10H14F3NO3
Molecular Weight	253.22 g/mol
Synonyms	(S)-1-Methylpropyl 3-[(Trifluoroacetyl)amino]propanoate; (S)-sec-Butyl 3-[(Trifluoroacetyl)amino]propanoate; β-Alanine, N-(trifluoroacetyl)-, (S)-1-methylpropyl ester; N-(Trifluoroacetyl)-β-alanine (S)-sec-butyl ester; (S)-sec-Butyl N-trifluoroacetyl-β-alaninate
EINECS	Contact for details

Quality Control

Our n-(Trifluoroacetyl)-β-Alanine (S)-1-Methylpropyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is stable under inert atmosphere. Keep away from strong bases and incompatible materials such as oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.