Description

6-Aminohexanoic Acid n-Hydroxysuccinimide Ester Matrix is a high-purity, bifunctional cross-linking reagent widely used in bioconjugation and protein modification workflows. This compound is essential for creating stable amide bonds between primary amines and carboxyl groups, enabling the precise attachment of biomolecules, labels, and solid supports. It is a critical material for researchers and manufacturers in the fields of biopharmaceutical development, diagnostic assay production, and advanced materials science.

Application

• Bioconjugation and Protein Labeling: Primary reagent for covalently linking proteins, peptides, or antibodies to enzymes, fluorophores, or other functional molecules.
• Immunoassay Development: Used in the preparation of enzyme-antibody conjugates for ELISA and other diagnostic test kits.
• Affinity Chromatography Matrix Preparation: Key intermediate for immobilizing ligands (e.g., proteins, peptides) onto agarose or other solid supports for purification columns.
• Drug Delivery Systems: Facilitates the site-specific attachment of therapeutic payloads to carrier molecules like antibodies (ADC development) or polymers.
• Biomaterial and Surface Functionalization: Enables the covalent modification of surfaces (e.g., biosensors, microarrays) with bioactive molecules for enhanced specificity.
• Cross-linking Agent: Used in the study of protein-protein interactions and the stabilization of macromolecular complexes.

Basic Information

Item	Detail
Product Name	6-Aminohexanoic Acid n-Hydroxysuccinimide Ester Matrix
CAS No.	55128-01-3
Molecular Formula	C10H14N2O4
Molecular Weight	226.23 g/mol
Synonyms	6-((2,5-Dioxopyrrolidin-1-yl)oxy)-6-oxohexan-1-aminium; N-Hydroxysuccinimide ester of 6-Aminohexanoic Acid; NHS-Ahx; Ahx-NHS ester; ε-Aminocaproic acid N-hydroxysuccinimide ester; N-Succinimidyl 6-aminocaproate; 6-Aminohexanoic Acid NHS Ester; N-(6-Aminohexanoyloxy)succinimide
EINECS	Contact for details

Quality Control

Our 6-Aminohexanoic Acid n-Hydroxysuccinimide Ester Matrix is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance for sensitive bioconjugation applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive). For long-term stability, store desiccated at -20°C. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMF, DMSO; Slightly soluble in acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.