Description

(E)-3-Methyl-2-Pentenedioic Acid Bis(Trimethylsilyl) Ester is a high-purity, protected derivative of a substituted pentenedioic acid, specifically designed for advanced synthetic chemistry. This compound is valued for its role as a key synthetic intermediate and protecting group reagent, enabling complex organic transformations under mild conditions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Organosilicon Chemistry: Acts as a versatile reagent for introducing trimethylsilyl (TMS) protecting groups to carboxylic acid functionalities in complex molecules.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, fragrances, and advanced materials.
• Academic & Industrial R&D: A valuable tool for methodological development and exploratory synthesis in university and corporate research laboratories.
• Peptide Mimetics: Can be used in the synthesis of peptidomimetics and other bio-inspired compounds.

Basic Information

Item	Details
Product Name	(E)-3-Methyl-2-Pentenedioic Acid Bis(Trimethylsilyl) Ester
CAS No.	55125-08-1
Molecular Formula	C14H28O4Si2
Molecular Weight	316.54 g/mol
Synonyms	3-Methyl-2-pentenedioic Acid Bis(trimethylsilyl) Ester; (E)-3-Methylglutaconic Acid Bis(TMS) Ester; Bis(trimethylsilyl) (E)-3-Methyl-2-pentenedioate; 2-Pentenedioic acid, 3-methyl-, 1,5-bis(trimethylsilyl) ester, (E)-; TMS Ester of 3-Methylglutaconic Acid; Glutaconic acid, 3-methyl-, bis(trimethylsilyl) ester
EINECS	Contact for details

Quality Control

Our (E)-3-Methyl-2-Pentenedioic Acid Bis(Trimethylsilyl) Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.