Description

n-Acetyl-n-(Trimethylsilyl)Glycine Trimethylsilyl Ester is a specialized organosilicon-protected amino acid derivative, primarily utilized as a key synthetic intermediate. Its value lies in providing a protected glycine moiety that is stable under various reaction conditions, enabling complex peptide and heterocycle synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reactive building blocks for sophisticated organic synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel peptide-based drugs, prodrugs, and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators requiring specific amino acid motifs.
• Peptide Chemistry: Serves as a protected glycine equivalent in solid-phase and solution-phase peptide synthesis (SPPS), facilitating the construction of complex peptide chains.
• Organosilicon Chemistry Research: A valuable reagent for studying silyl group transfer reactions and the stability of silylated amino acids.
• Material Science: Potential precursor for functionalized surfaces or silicon-containing polymers with tailored properties.
• Chemical Derivatization: Used in analytical chemistry to enhance the volatility and detectability of amino acids in GC-MS analysis.

Basic Information

Product Name	n-Acetyl-n-(Trimethylsilyl)Glycine Trimethylsilyl Ester
CAS No.	55124-99-7
Molecular Formula	C10H21NO3Si2
Molecular Weight	247.45 g/mol
Synonyms	N-Acetyl-N-(trimethylsilyl)glycine trimethylsilyl ester; N-(Trimethylsilyl)-N-acetylglycine trimethylsilyl ester; Ac-TMS-Gly-OTMS; (Trimethylsilyl)[(trimethylsilyloxy)carbonylmethyl]acetamide; N-Acetylglycine, N-(trimethylsilyl)-, trimethylsilyl ester; TMS-Gly(O-TMS)-Ac; N-(Trimethylsilyl)-2-[(trimethylsilyl)oxy]-2-oxoethanaminium
EINECS	Contact for details

Quality Control

Our n-Acetyl-n-(Trimethylsilyl)Glycine Trimethylsilyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high chemical purity and identity. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and highly volatile nature, store under an inert atmosphere (argon or nitrogen) in a cool, dry place at 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress and condensation. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.