Description

3-[(Trimethylsilyl)Oxy]Isovaleric Acid Trimethylsilyl Ester is a specialized organosilicon reagent featuring dual silyl-protecting groups, making it a versatile intermediate in advanced organic synthesis. Its primary value lies in its ability to protect carboxylic acid and hydroxyl functionalities simultaneously, enabling complex multi-step reactions with high selectivity and yield. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, reliable building blocks for synthesizing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those requiring protected functional groups during multi-step sequences.
• Peptide Synthesis: Used as a protecting agent for carboxylic acids in solid-phase and solution-phase peptide chemistry.
• Agrochemical Production: Intermediate in the manufacture of advanced pesticides and herbicides where specific functional group manipulation is required.
• Fine Chemical Synthesis: Serves as a precursor or protecting group reagent in the production of flavors, fragrances, and specialty materials.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and catalysis research.
• Silicon-Containing Polymer Research: Potential monomer or modifier in the development of novel silicone-based polymeric materials.

Basic Information

Product Name	3-[(Trimethylsilyl)Oxy]Isovaleric Acid Trimethylsilyl Ester
CAS No.	55124-90-8
Molecular Formula	C11H26O3Si2
Molecular Weight	262.50 g/mol
Synonyms	3-(Trimethylsiloxy)isovaleric Acid Trimethylsilyl Ester; Isovaleric Acid, 3-(Trimethylsiloxy)-, Trimethylsilyl Ester; Trimethylsilyl 3-(Trimethylsiloxy)-3-methylbutanoate; 3-Methyl-3-(trimethylsiloxy)butanoic Acid Trimethylsilyl Ester; Bis(trimethylsilyl) 3-Hydroxy-3-methylbutyrate; TMS-Protected 3-Hydroxyisovalerate
EINECS	Contact for details

Quality Control

Our production of 3-[(Trimethylsilyl)Oxy]Isovaleric Acid Trimethylsilyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full transparency and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.