Description

2-(Trimethylsilylamino)-3-[(Trimethylsilyl)Amino]Propionic Acid Trimethylsilyl Ester is a specialized organosilicon reagent featuring multiple silyl-protected functional groups. This compound is valued for its role as a key synthetic intermediate and protecting group agent in advanced organic synthesis. It is primarily sought by research and development chemists in the pharmaceutical and fine chemical industries for constructing complex molecules, particularly peptides and modified amino acids.

Application

• Advanced Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) and peptide-based drugs.
• Peptide Synthesis & Modification: Used as a protecting group reagent for amino and carboxylic acid functionalities, enabling selective reactions in complex peptide chain assembly.
• Fine Chemical Manufacturing: Acts as a versatile intermediate in the production of high-value specialty chemicals, agrochemicals, and performance materials.
• Organosilicon Chemistry Research: A valuable reagent for academic and industrial research exploring new silylation reactions and the development of silicon-containing compounds.
• Process Chemistry & Scale-up: Employed in route development and optimization for the efficient, large-scale production of target molecules.

Basic Information

Product Name	2-(Trimethylsilylamino)-3-[(Trimethylsilyl)Amino]Propionic Acid Trimethylsilyl Ester
CAS No.	55124-76-0
Molecular Formula	C14H36N2O2Si3
Molecular Weight	348.71 g/mol
Synonyms	Bis(trimethylsilyl)-L-asparagine trimethylsilyl ester; 3-[(Trimethylsilyl)amino]-2-(trimethylsilylamino)propionic acid trimethylsilyl ester; L-Asparagine, N2,N3-bis(trimethylsilyl)-, trimethylsilyl ester; TMS-Asparagine TMS ester; Nα,Nβ-Bis(trimethylsilyl)-L-asparagine O-trimethylsilyl ester; 2,3-Bis(trimethylsilylamino)propionic acid trimethylsilyl ester
EINECS	Contact for details

Quality Control

Our production of 2-(Trimethylsilylamino)-3-[(Trimethylsilyl)Amino]Propionic Acid Trimethylsilyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and purity for sensitive synthetic applications. Each lot undergoes comprehensive analysis, including assay by GC or HPLC and identity confirmation by spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after initial opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 95.0%
Purity (by GC)	≥ 97.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.