Description

6-(7-Chloro-1,8-Naphthyridin-2-Yl)-5H-Pyrrolo[3,4-B]Pyrazine-5,7(6H)-Dione is a high-purity, heterocyclic organic compound serving as a critical advanced intermediate in pharmaceutical research and development. Its complex fused-ring structure makes it a valuable building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. This compound is primarily sought after by research institutions, contract research organizations (CROs), and pharmaceutical companies engaged in the discovery of new drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules and novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Heterocyclic Compound Synthesis: Serves as a versatile precursor for creating more complex fused-ring systems in organic synthesis.
• Kinase Inhibitor Development: Potential scaffold for the research and development of kinase-targeted therapies due to its naphthyridine and pyrazine motifs.
• Chemical Biology Probes: Can be utilized in the design of molecular probes for studying biological pathways and target identification.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	6-(7-Chloro-1,8-Naphthyridin-2-Yl)-5H-Pyrrolo[3,4-B]Pyrazine-5,7(6H)-Dione
CAS No.	55112-93-1
Molecular Formula	C14H7ClN4O2
Molecular Weight	298.68 g/mol
Synonyms	6-(7-Chloro-1,8-naphthyridin-2-yl)-5H-pyrrolo[3,4-b]pyrazine-5,7(6H)-dione; 7-Chloro-2-(5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyrazin-6-yl)-1,8-naphthyridine; 6-(7-Chloro-1,8-naphthyridin-2-yl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine-5,7-dione; 55112-93-1; 6-(7-chloro-1,8-naphthyridin-2-yl)-5H-pyrrolo[3,4-b]pyrazine-5,7(6H)-dione; 6-(7-chloro-1,8-naphthyridin-2-yl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine-5,7-dione
EINECS	Contact for details

Quality Control

Our 6-(7-Chloro-1,8-Naphthyridin-2-Yl)-5H-Pyrrolo[3,4-B]Pyrazine-5,7(6H)-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, and custom purity grades are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.