Description

[1-[(2,2-Dimethylpropylidene)Amino]Butyl]Phosphonic Acid Bis(Trimethylsilyl) Ester is a specialized organophosphorus compound featuring a silyl-protected phosphonic acid group and a sterically hindered imine moiety. This unique structure makes it a valuable protected intermediate or reagent in advanced organic synthesis, particularly for the controlled introduction of phosphonate functionality. It is primarily utilized by pharmaceutical and agrochemical R&D teams for constructing complex molecules, including potential active ingredients and novel ligands for catalysis.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those requiring phosphonate or phosphonic acid pharmacophores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, or plant growth regulators where the phosphonate group is critical for bioactivity.
• Ligand Precursor: Acts as a precursor for sophisticated chelating ligands in coordination chemistry and homogeneous catalysis.
• Material Science Research: Employed in the development of functionalized surfaces, metal-organic frameworks (MOFs), or novel polymers.
• Process Chemistry: The trimethylsilyl (TMS) protecting groups allow for selective reactions, making it useful in multi-step synthetic routes in process development.

Basic Information

Product Name	[1-[(2,2-Dimethylpropylidene)Amino]Butyl]Phosphonic Acid Bis(Trimethylsilyl) Ester
CAS No.	55108-75-3
Molecular Formula	C15H36NO3PSi2
Molecular Weight	365.60 g/mol
Synonyms	(1-[(2,2-Dimethylpropylidene)amino]butyl)phosphonic acid bis(trimethylsilyl) ester; Phosphonic acid, P-[1-[(2,2-dimethylpropylidene)amino]butyl]-, bis(trimethylsilyl) ester; Bis(trimethylsilyl) [1-[(2,2-dimethylpropylidene)amino]butyl]phosphonate; 55108-75-3; P-[1-[(2,2-Dimethylpropylidene)amino]butyl]phosphonic acid bis(trimethylsilyl) ester; TMS-protected phosphonate; Neopentylideneamino butylphosphonate bis(TMS) ester
EINECS	Contact for details

Quality Control

Every batch of [1-[(2,2-Dimethylpropylidene)Amino]Butyl]Phosphonic Acid Bis(Trimethylsilyl) Ester is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards for research and process chemistry. Comprehensive analytical data, including HPLC, NMR, and GC, is generated to verify identity, purity, and stability. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.