Description

[1-[(2,2-Dimethylpropylidene)Amino]Propyl]Phosphonic Acid Bis(Trimethylsilyl) Ester is a specialized organophosphorus compound featuring a protected phosphonic acid group, making it a valuable intermediate in advanced organic synthesis. Its primary commercial value lies in its role as a key building block for the preparation of phosphonate derivatives, which are crucial in the development of pharmaceuticals, agrochemicals, and functional materials. This high-purity intermediate is essential for research and production chemists in fine chemical, pharmaceutical, and material science industries seeking to incorporate phosphonate functionality into complex molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of bioactive molecules, including potential enzyme inhibitors and prodrugs with phosphonate groups.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, pesticides, and plant growth regulators containing phosphonate moieties.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized phosphonate-based ligands used in metal catalysis and coordination chemistry.
• Material Science: Building block for surface-modifying agents, flame retardants, and additives for polymers and composites.
• Peptide Mimetics: Employed in medicinal chemistry for the synthesis of phosphonate-based peptide analogs and transition-state inhibitors.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new synthetic methodologies involving protected phosphonic acids.

Basic Information

Product Name	[1-[(2,2-Dimethylpropylidene)Amino]Propyl]Phosphonic Acid Bis(Trimethylsilyl) Ester
CAS No.	55108-74-2
Molecular Formula	C14H34NO3PSi2
Molecular Weight	351.57 g/mol
Synonyms	(3-((2,2-Dimethylpropylidene)amino)propyl)phosphonic acid bis(trimethylsilyl) ester; Phosphonic acid, P-[3-[(2,2-dimethylpropylidene)amino]propyl]-, bis(trimethylsilyl) ester; Bis(trimethylsilyl) (3-((2,2-dimethylpropylidene)amino)propyl)phosphonate; N-(2,2-Dimethylpropylidene)-3-[(bis(trimethylsilyl)oxy)phosphinyl]-1-propanamine; TMS-protected phosphonate intermediate
EINECS	Contact for details

Quality Control

Our production of [1-[(2,2-Dimethylpropylidene)Amino]Propyl]Phosphonic Acid Bis(Trimethylsilyl) Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including NMR, HPLC, and GC analysis, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.