Description

[3-(Isopropylideneamino)Propyl]Phosphonic Acid Bis(Trimethylsilyl) Ester CAS NO 55108-72-0 is a specialized organophosphorus compound featuring both phosphonic acid ester and imine functional groups, protected by trimethylsilyl groups. This unique structure makes it a valuable protected synthon and key intermediate in advanced organic synthesis, particularly for introducing phosphonate moieties under mild conditions. It is essential for pharmaceutical research, agrochemical development, and materials science, where precise molecular construction is critical.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those targeting bone diseases or requiring phosphonate-based bioisosteres.
• Agrochemical Synthesis: Serves as a key building block for creating herbicides, plant growth regulators, and fungicides with phosphonic acid activity.
• Ligand and Catalyst Preparation: Employed in the development of specialized phosphonate-based ligands for metal catalysis and coordination chemistry.
• Surface Modification Agent: Used to functionalize metal oxides and other surfaces, imparting specific chemical properties for advanced materials.
• Flame Retardant Synthon: Acts as an intermediate in the production of phosphorus-containing flame retardants for polymers and textiles.
• Peptide Mimetics Research: Utilized to incorporate hydrolytically stable phosphonate groups into peptide backbones for medicinal chemistry applications.

Basic Information

Item	Details
Product Name	[3-(Isopropylideneamino)Propyl]Phosphonic Acid Bis(Trimethylsilyl) Ester
CAS No.	55108-72-0
Molecular Formula	C12H30NO3PSi2
Molecular Weight	323.52 g/mol
Synonyms	Bis(trimethylsilyl) [3-(isopropylideneamino)propyl]phosphonate; (3-Isopropylideneaminopropyl)phosphonic Acid Bis(trimethylsilyl) Ester; Phosphonic Acid, P-[3-[(1-Methylethylidene)amino]propyl]-, Bis(trimethylsilyl) Ester; 55108-72-0; N-(1-Methylethylidene)-3-[(bis(trimethylsilyl)oxy)phosphinyl]-1-propanamine; Silylated Phosphonate Imine
EINECS	Contact for details

Quality Control

Our production of [3-(Isopropylideneamino)Propyl]Phosphonic Acid Bis(Trimethylsilyl) Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and industrial use. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with each shipment. We support custom synthesis and purity grade tailoring to meet specific project requirements from milligram to kilogram scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis of the silyl ester groups. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC or HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.