Description

[2-Methyl-1-(Isopropylideneamino)Propyl]Phosphonic Acid Bis(Trimethylsilyl) Ester CAS NO 55108-68-4 is a specialized organophosphorus compound featuring a phosphonic acid core protected by trimethylsilyl (TMS) groups and an isopropylideneamino moiety. This unique structure makes it a valuable protected intermediate or reagent in advanced organic synthesis, particularly for introducing phosphorus-containing functional groups under mild conditions. It is primarily needed by pharmaceutical researchers, agrochemical developers, and specialty chemical manufacturers for constructing complex molecules, including potential bioactive agents and ligands.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those requiring phosphonate or phosphonic acid ester functionalities.
• Agrochemical Synthesis: Serves as a key building block for creating advanced herbicides, insecticides, or plant growth regulators with phosphorus-based active sites.
• Ligand Precursor: Employed in organometallic chemistry and catalysis research for the preparation of sophisticated phosphorus-containing ligands.
• Peptide Mimetics & Prodrug Development: Utilized to incorporate hydrolytically stable phosphonate analogs or to create prodrug forms of phosphonic acid-based therapeutics.
• Material Science Research: Acts as a monomer or modifying agent in the development of specialty polymers and advanced materials with specific surface properties.
• Process Chemistry: Functions as a protected phosphonate reagent in multi-step industrial-scale synthesis, where its stability is advantageous.

Basic Information

Item	Detail
Product Name	[2-Methyl-1-(Isopropylideneamino)Propyl]Phosphonic Acid Bis(Trimethylsilyl) Ester
CAS No.	55108-68-4
Molecular Formula	C13H32NO3PSi2
Molecular Weight	337.55 g/mol
Synonyms	Bis(trimethylsilyl) [2-methyl-1-[(propan-2-ylidene)amino]propyl]phosphonate; Phosphonic acid, P-[2-methyl-1-[(1-methylethylidene)amino]propyl]-, bis(trimethylsilyl) ester; (Isopropylideneamino-2-methylpropyl)phosphonic acid bis(trimethylsilyl) ester; TMS-protected phosphonate; N-(2-Methyl-1-phosphonopropyl)acetone imine bis(trimethylsilyl) ester
EINECS	Contact for details

Quality Control

Our production of [2-Methyl-1-(Isopropylideneamino)Propyl]Phosphonic Acid Bis(Trimethylsilyl) Ester adheres to stringent internal quality protocols. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by NMR or HPLC), identity (IR, NMR), and purity profile are available upon request. We are committed to supplying material that meets the exacting standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition upon exposure to atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (by 1H NMR or HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.